Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]
Chromosome XII: 849,866-852,019 forward strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 399 orthologues and 9 paralogues.