Adenylosuccinate lyase; catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency; human ADSL can complement yeast ADE13 null mutant [Source:SGD;Acc:S000004351]

BRA1, BRA8

Chromosome XII: 844,282-845,730 forward strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 274 orthologues and is a member of 1 Ensembl protein family.

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