Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; protein abundance increases in response to DNA replication stress; ORM2 has a paralog, ORM1, that arose from the whole genome duplication [Source:SGD;Acc:S000004342]

Chromosome XII: 828,730-829,380 forward strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 327 orthologues and 1 paralogue.

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