Membrane bound guanine nucleotide exchange factor; also known as a GEF or GDP-release factor; indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1; thermosensitivity of the cdc25-5 mutant is functionally complemented by human RASGRF1 or by a fragment of human SOS1 comprising the CDC25-related catalytic domain [Source:SGD;Acc:S000004301]

CDC25', CTN1

Chromosome XII: 752,224-756,993 reverse strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 457 orthologues and 2 paralogues.

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