Membrane bound guanine nucleotide exchange factor; also known as a GEF or GDP-release factor; indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1; thermosensitivity of the cdc25-5 mutant is functionally complemented by human RASGRF1 or by a fragment of human SOS1 comprising the CDC25-related catalytic domain [Source:SGD;Acc:S000004301]
CDC25', CTN1
Chromosome XII: 752,224-756,993 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 457 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.