Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p; a fraction is localized, with Vps15p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery [Source:SGD;Acc:S000004230]
END12, PEP15, STT8, VPL7, VPS7, VPT29
Chromosome XII: 617,533-620,160 forward strand.
This gene has 1 transcript (splice variant), 353 orthologues and 2 paralogues.
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