Assembly factor for the eIF2 translation initiation factor complex; regulates translational initiation; conserved residues of this ATP-Grasp protein that bind to ATP-Mg2+ in the pombe ortholog are required for complex assembly in budding yeast; interaction with eIF2 subunit Gcd11p facilitates complex assembly and activity; required for the START transition and timely progression through G2; regulated by nutrient availability; human ortholog complements the yeast mutant [Source:SGD;Acc:S000004205]
Chromosome XII: 570,776-571,858 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 344 orthologues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
CDC123 | YLR215C_mRNA | 1083 | 360aa | YLR215C | Protein coding | Q05791 | - | Ensembl Canonical, |