Assembly factor for the eIF2 translation initiation factor complex; regulates translational initiation; conserved residues of this ATP-Grasp protein that bind to ATP-Mg2+ in the pombe ortholog are required for complex assembly in budding yeast; interaction with eIF2 subunit Gcd11p facilitates complex assembly and activity; required for the START transition and timely progression through G2; regulated by nutrient availability; human ortholog complements the yeast mutant [Source:SGD;Acc:S000004205]

Chromosome XII: 570,776-571,858 reverse strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 344 orthologues and is a member of 1 Ensembl protein family.

Show transcript tableHide transcript table