Alanine transaminase (glutamic pyruvic transaminase); involved in alanine biosynthesis and catabolism; TOR1-independent role in determining chronological lifespan; expression is induced in the presence of alanine; repression is mediated by Nrg1p; ALT1 has a paralog, ALT2, that arose from the whole genome duplication; Alt2p is catalytically inactive [Source:SGD;Acc:S000004079]
Chromosome XII: 318,237-320,015 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 387 orthologues, 6 paralogues and is a member of 1 Ensembl protein family.