Protein involved in SRP-independent targeting of substrates to the ER; component of an alternative ER targeting pathway that has partial functional redundancy with the GET pathway; preference for substrates with downstream transmembrane domains; interacts with Snd1p, Pho88p/Snd3p, and Sec61p-translocon subunits; can compensate for loss of SRP; role in the late endosome-vacuole interface; putative role in secretory protein quality control [Source:SGD;Acc:S000004055]
Chromosome XII: 266,373-266,918 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 282 orthologues and is a member of 1 Ensembl protein family.