C-5 sterol desaturase; glycoprotein that catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; transcriptionally down-regulated when ergosterol is in excess; mutants are viable, but cannot grow on non-fermentable carbon sources; substrate of HRD ubiquitin ligase; mutation is functionally complemented by human SC5D [Source:SGD;Acc:S000004046]

PSO6, SYR1

Chromosome XII: 253,861-254,958 forward strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 279 orthologues and 2 paralogues.

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