Saccharomyces cerevisiae (R64-1-1)

Guanine nucleotide exchange factor (GEF) for Ria1p; essential protein involved in ribosome maturation; with Ria1p, promotes release of Tif6p from 60S ribosomal subunits in the cytoplasm so that they can assemble with 40S subunits to generate mature ribosomes; ortholog of the human protein (SBDS) responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome; highly conserved across archaea and eukaryotes [Source:SGD;Acc:S000004012]


Chromosome XII: 184,174-184,926 reverse strand.


About this gene

This gene has 1 transcript (splice variant) and 344 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
Q07953 -Ensembl Canonical