Ribosomal 60S subunit protein L8B; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8 S rRNAs; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8B has a paralog, RPL8A, that arose from the whole genome duplication [Source:SGD;Acc:S000003968]
KRB1, L4B, L8B, rp6, SCL41, YL5
Chromosome XII: 47,859-48,629 reverse strand.
This gene has 1 transcript (splice variant), 444 orthologues and 4 paralogues.
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