Saccharomyces cerevisiae (R64-1-1)
Description

Disaggregase; heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured, aggregated proteins; responsive to stresses including: heat, ethanol, and sodium arsenite; involved in [PSI+] propagation; protein becomes more abundant and forms cytoplasmic foci in response to DNA replication stress; potentiated Hsp104p variants decrease TDP-43 proteotoxicity by eliminating its cytoplasmic aggregation [Source:SGD;Acc:S000003949]

Location

Chromosome XII: 88,623-91,349 forward strand.

R64-1-1:BK006945.2

About this gene

This gene has 1 transcript (splice variant), 382 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
HSP104YLL026W_mRNA2727908aaYLL026W
 
Protein coding
P31539 NM_001181846.1
NP_013074.1

Gene-based displays