Aspartyl-tRNA synthetase, primarily cytoplasmic; homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation; shares five highly conserved amino acids with human that when mutated cause leukoencephalopathy characterized by hypomyelination with brain stem and spinal cord involvement and leg spasticity (HBSL) [Source:SGD;Acc:S000003941]

aspartyl-tRNA synthetase, AspRS

Chromosome XII: 109,902-111,575 reverse strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 272 orthologues and 5 paralogues.

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