Histone acetyltransferase; critical for cell survival in presence of DNA damage during S phase, required for recovery after DSB repair; acetylates H3K56, H3K9; H3K56 acetylation activity required for expression homeostasis, buffering of mRNA synthesis rate against changes in gene dosage during S phase; involved in non-homologous end joining and regulation of Ty1 transposition; prevents hyper-amplification of rDNA; interacts physically with Vps75p [Source:SGD;Acc:S000003925]

KAT11, KIM2, REM50

Chromosome XII: 146,291-147,601 forward strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 290 orthologues and is a member of 2 Ensembl protein families.

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