Saccharomyces cerevisiae (R64-1-1)

DEAH-box RNA helicase involved in second catalytic step of splicing and in exon ligation; exhibits ATP-dependent RNA unwinding activity; mediates the release of Yju2p and Cwc25p in the second step; in the absence of ATP, stabilizes the binding of Cwc25p to the spliceosome in the first catalytic step; missense mutation in human ortholog DHX38 associated with early-onset retinitis pigmentosa [Source:SGD;Acc:S000001794]

Gene Synonyms

PRP23, RNA16


Chromosome XI: 599,857-603,072 forward strand.


About this gene

This gene has 1 transcript (splice variant), 344 orthologues and 6 paralogues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P15938 -Ensembl Canonical