Alpha subunit of translation initiation factor eIF2B; guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; positive regulator of GCN4 expression; assembles into filaments with Gcd2p, Gcd6p, Gcd7p, and Sui2p as cells approach stationary phase and under cytosolic acidification and starvation conditions; human homolog EIF2B1 can complement yeast null mutant [Source:SGD;Acc:S000001734]

AAS2

Chromosome XI: 488,738-489,655 reverse strand.

R64-1-1:BK006944.2

This gene has 1 transcript (splice variant), 347 orthologues and 3 paralogues.

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