Monocarboxylate/proton symporter of the plasma membrane; transport activity is dependent on the pH gradient across the membrane; mediates high-affinity uptake of carbon sources lactate, pyuvate, and acetate, and also of the micronutrient selenite, whose structure mimics that of monocarboxylates; expression and localization are tightly regulated, with transcription repression, mRNA degradation, and protein endocytosis and degradation all occurring in the presence of glucose [Source:SGD;Acc:S000001700]
Chromosome XI: 22,234-24,084 forward strand.
R64-1-1:BK006944.2
This gene has 1 transcript (splice variant), 372 orthologues and 31 paralogues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
JEN1 | YKL217W_mRNA | 1851 | 616aa | YKL217W | Protein coding | P36035 | - | Ensembl Canonical, |