Plasma membrane ATP-binding cassette (ABC) transporter; required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells; human homolog ABCB1 mediates multidrug resistance in many chemotherapy-resistant tumors by effluxing toxic compounds from the cell [Source:SGD;Acc:S000001692]

Chromosome XI: 42,423-46,295 reverse strand.

R64-1-1:BK006944.2

This gene has 1 transcript (splice variant), 287 orthologues and is a member of 2 Ensembl protein families.

Show transcript tableHide transcript table