Import and assembly protein in mitochondrial intermembrane space; component of MIA pathway which mediates import and oxidative folding of substrates including small proteins containing twin cysteine motifs; acts in concert with Erv1p, which oxidizes the cysteine residues of Mia40p to comprise a disulfide relay system that catalyzes import; also mediates folding of Atp23p via a chaperone-like activity; forms a dimer that binds iron-sulfur cluster in vitro [Source:SGD;Acc:S000001678]
FMP15, TIM40
Chromosome XI: 75,821-77,032 forward strand.
R64-1-1:BK006944.2
This gene has 1 transcript (splice variant), 335 orthologues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
MIA40 | YKL195W_mRNA | 1212 | 403aa | YKL195W | Protein coding | P36046 | - | Ensembl Canonical, |