Saccharomyces cerevisiae (R64-1-1)
Description

5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; plays a key role in cell wall integrity (CWI) pathway; one of five related enzymes, which are active as heteromultimeric complexes; missense mutations in human homolog PRPS1 are associated with neuropathic Arts syndrome and Charcot-Marie Tooth (CMTX5) disease [Source:SGD;Acc:S000001664]

Gene Synonyms

PRP1

Location

Chromosome XI: 107,316-108,599 forward strand.

R64-1-1:BK006944.2

About this gene

This gene has 1 transcript (splice variant), 380 orthologues and 4 paralogues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
PRS1YKL181W_mRNA1284427aaYKL181W
 
Protein coding
P32895 -Ensembl Canonical