Flavoprotein subunit of succinate dehydrogenase; couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain; FAD binding to Sdh1p is required for the assembly of the succinate dehydrogenase subunits; mutations in human ortholog SDHA are associated with Leigh syndrome [Source:SGD;Acc:S000001631]
SDHA
Chromosome XI: 169,207-171,129 reverse strand.
R64-1-1:BK006944.2
This gene has 1 transcript (splice variant), 259 orthologues, 3 paralogues and is a member of 1 Ensembl protein family.