Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]

Chromosome XI: 182,958-184,544 forward strand.

R64-1-1:BK006944.2

This gene has 1 transcript (splice variant), 350 orthologues, 6 paralogues and is a member of 1 Ensembl protein family.

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