Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA; structure reveals unique HEAT repeat fold and a surface serine patch; phosphorylation of serine patch impairs cell growth and reduces RNA polymerase I binding in vitro and RNA polymerase I recruitment to the rDNA gene in vivo [Source:SGD;Acc:S000001608]

Chromosome XI: 208,247-210,130 forward strand.

R64-1-1:BK006944.2

This gene has 1 transcript (splice variant), 232 orthologues and is a member of 2 Ensembl protein families.

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