Major apurinic/apyrimidinic endonuclease; 3'-repair diesterase; involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine; genetically interacts with NTG1 to maintain mitochondrial genome integrity [Source:SGD;Acc:S000001597]
Chromosome XI: 223,352-224,455 reverse strand.
R64-1-1:BK006944.2
This gene has 1 transcript (splice variant), 323 orthologues and is a member of 2 Ensembl protein families.