Saccharomyces cerevisiae (R64-1-1)
Description

Intramembrane aspartyl protease of the perinuclear ER membrane; acts in a branch of ER-associated degradation (ERAD) that degrades functional proteins rather than misfolded proteins; regulates abundance of high-affinity plasma membrane transporters, such as Ctr1p and Zrt1p, during the starvation response; has a presenilin fold; member of the GxGD family of intramembrane proteases; closest human homolog is signal peptide peptidase (SPP) [Source:SGD;Acc:S000001583]

Location

Chromosome XI: 253,697-255,460 reverse strand.

R64-1-1:BK006944.2

About this gene

This gene has 1 transcript (splice variant), 286 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
YPF1YKL100C_mRNA1764587aaYKL100C
 
Protein coding
P34248 NM_001179666.1
NP_012822.1

Gene-based displays