Saccharomyces cerevisiae (R64-1-1)
Description

Transcriptional repressor that regulates hypoxic genes during normoxia; involved in the aerobic repression of genes such as COX5b, TIR1, and HEM13; binds DNA intrastrand cross-links formed by cisplatin; HMG (high mobility group box) domain containing protein which binds and bends cisplatin-modified DNA, blocking excision repair; IXR1 has a paralog, ABF2, that arose from the whole genome duplication [Source:SGD;Acc:S000001515]

Synonyms

ORD1

Location

Chromosome XI: 380,065-381,858 reverse strand.

R64-1-1:BK006944.2

About this gene

This gene has 1 transcript (splice variant), 32 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
IXR1YKL032C_mRNA1794597aaYKL032C
 
Protein coding
P33417 NM_001179598.3
NP_012893.3

Gene-based displays