Subunit of the anaphase-promoting complex/cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; required for sporulation; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000001505]
Chromosome XI: 394,726-397,248 reverse strand.
R64-1-1:BK006944.2
This gene has 1 transcript (splice variant), 343 orthologues and 2 paralogues.