JmjC domain family histone demethylase; promotes global demethylation of H3K4 and repression of noncoding intergenic transcription during sporulation; removes methyl groups added by Set1p methyltransferase; negatively regulated by H3K14 acetylation; protein levels regulated by Not4p polyubiquitin-mediated degradation; regulates sporulation timing by extending period of active transcription in opposition to programmed global transcriptional quiescence; regulates rDNA silencing [Source:SGD;Acc:S000003880]
KDM5
Chromosome X: 644,304-646,490 reverse strand.
R64-1-1:BK006943.2
This gene has 1 transcript (splice variant), 361 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
JHD2 | YJR119C_mRNA | 2187 | 728aa | YJR119C | Protein coding | P47156 | - | Ensembl Canonical, |