Essential ATP-binding protein required for DNA replication; component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p; relocalizes from nucleus to cytoplasm upon DNA replication stress; degraded in response to plasma membrane stress [Source:SGD;Acc:S000003730]

Chromosome X: 69,338-70,879 forward strand.

R64-1-1:BK006943.2

This gene has 1 transcript (splice variant), 354 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.

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