Saccharomyces cerevisiae (R64-1-1)
Description

Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36 (H3K36), which suppresses incorporation of acetylated histones and signals for the deacetylation of these histones within transcribed genes; associates with the C-terminal domain(CTD) of Rpo21p; H3K36me3 (trimethylation) requires Spt6p, proline 38 on H3, CTD of Rpo21p, Ctk1p, and C-terminal SRI domain of Ste2p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003704]

Synonyms

EZL1, KMT3

Location

Chromosome X: 102,227-104,428 reverse strand.

R64-1-1:BK006943.2

About this gene

This gene has 1 transcript (splice variant), 299 orthologues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SET2YJL168C_mRNA2202733aaYJL168C
 
Protein coding
P46995 NM_001181601.2
NP_012367.2

Gene-based displays