Saccharomyces cerevisiae (R64-1-1)
Description

cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]

Synonyms

PKA1, SRA3

Location

Chromosome X: 109,966-111,159 reverse strand.

R64-1-1:BK006943.2

About this gene

This gene has 1 transcript (splice variant), 50 orthologues, 2 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
TPK1YJL164C_mRNA1194397aaYJL164C
 
Protein coding
P06244 NM_001181597.2
NP_012371.2

Gene-based displays