cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]
PKA1, SRA3
Chromosome X: 109,966-111,159 reverse strand.
R64-1-1:BK006943.2
This gene has 1 transcript (splice variant), 409 orthologues, 3 paralogues and is a member of 1 Ensembl protein family.
| Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|
| TPK1 | YJL164C_mRNA | 1194 | 397aa | YJL164C | Protein coding | P06244 | - | Ensembl Canonical, |





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