Saccharomyces cerevisiae (R64-1-1)
Description

ATP-dependent 3'-5' RNA helicase of the DExD/H family; involved in nuclear RNA processing and degradation both as a component of TRAMP complex and in TRAMP-independent processes; TRAMP unwinds RNA duplexes, with Mtr4p unwinding activity stimulated by Pap2p/Air2p but not dependent on ongoing polyadenylation; contains an arch domain, with two coiled-coil arms/stalks and a globular fist/KOW domain, which has RNA binding activity and is required for 5.8S rRNA processing [Source:SGD;Acc:S000003586]

Synonyms

DOB1

Location

Chromosome X: 342,522-345,743 forward strand.

R64-1-1:BK006943.2

About this gene

This gene has 1 transcript (splice variant), 229 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
MTR4YJL050W_mRNA32221073aaYJL050W
 
Protein coding
P47047 NM_001181483.1
NP_012485.1

Gene-based displays