3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase; 3PG dehydrogenase that catalyzes the first step in serine and glycine biosynthesis; also functions as an alpha-ketoglutarate reductase, converting alpha-ketoglutarate to D-2-hydroxyglutarate (D-2HG); localizes to the cytoplasm; SER33 has a paralog, SER3, that arose from the whole genome duplication [Source:SGD;Acc:S000001336]
Chromosome IX: 221,081-222,490 reverse strand.
R64-1-1:BK006942.2
This gene has 1 transcript (splice variant), 366 orthologues, 5 paralogues and is a member of 1 Ensembl protein family.