Nuclear response regulator and transcription factor; physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets; part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; involved in osmoregulation; relocalizes to the cytosol in response to hypoxia; SKN7 has a paralog, HMS2, that arose from the whole genome duplication [Source:SGD;Acc:S000001249]
BRY1, POS9
Chromosome VIII: 512,732-514,600 forward strand.
R64-1-1:BK006934.2
This gene has 1 transcript (splice variant), 119 orthologues and 3 paralogues.