Autophagy-related protein and dual specificity member of the E1 family; mediates the attachment of Atg12p to Atg5p and Atg8p to phosphatidylethanolamine which are required steps in autophagosome formation; E1 enzymes are also known as ubiquitin-activating enzymes; involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner [Source:SGD;Acc:S000001214]

APG11, APG7, CVT2

Chromosome VIII: 445,713-447,605 forward strand.

R64-1-1:BK006934.2

This gene has 1 transcript (splice variant), 357 orthologues and 7 paralogues.

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