Saccharomyces cerevisiae (R64-1-1)

Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; forms foci at the nuclear periphery upon DNA replication stress; relocalizes to the cytosol in response to hypoxia; homolog of mammalian INSIG proteins; NSG1 has a paralog, NSG2, that arose from the whole genome duplication [Source:SGD;Acc:S000001175]


Chromosome VIII: 370,722-371,597 reverse strand.


About this gene

This gene has 1 transcript (splice variant), 190 orthologues and 1 paralogue.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P38837 -Ensembl Canonical