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Saccharomyces cerevisiae (R64-1-1)
Description

Histone methyltransferase, subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3K4; Set1p-dependent H3K4 trimethylation recruits Nrd1p, allowing efficient termination of snoRNAs and cryptic unstable transcripts (CUTs) by Nrd1p-Nab3p-Sen1p pathway; modulates histone acetylation levels in promoter proximal regions to ensure efficient Nrd1p-dependent termination; required in transcriptional silencing near telomeres and at silent mating type loci; has a SET domain [Source:SGD;Acc:S000001161]

Gene Synonyms

KMT2, YTX1

Location

Chromosome VIII: 346,043-349,285 forward strand.

R64-1-1:BK006934.2

About this gene

This gene has 1 transcript (splice variant), 345 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SET1YHR119W_mRNA32431080aaYHR119W
 
Protein coding
P38827 -Ensembl Canonical