Saccharomyces cerevisiae (R64-1-1)
Description

Ubiquitin-protein ligase (E3); controls septin dynamics, spindle position checkpoint (SPOC) with ligase Dma2p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ubiquitinates cyclin Pcl1p; ortholog of human RNF8, similar to human Chfr; contains FHA, RING fingers; DMA1 has a paralog, DMA2, that arose from the whole genome duplication [Source:SGD;Acc:S000001157]

Synonyms

CHF1

Location

Chromosome VIII: 340,109-341,359 reverse strand.

R64-1-1:BK006934.2

About this gene

This gene has 1 transcript (splice variant), 298 orthologues, 3 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
DMA1YHR115C_mRNA1251416aaYHR115C
 
Protein coding
P38823 NM_001179245.1
NP_011983.1

Gene-based displays