Saccharomyces cerevisiae (R64-1-1)
Description

Essential nuclear envelope/ER integral membrane protein; interacts and functions with Apq12p and Brr6p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, mRNA nuclear export and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; identified as a dosage suppressor of a temperature sensitive mutation in the major karyopherin, CRM1; homologous to Brr6p [Source:SGD;Acc:S000001078]

Location

Chromosome VIII: 180,345-181,760 forward strand.

R64-1-1:BK006934.2

About this gene

This gene has 1 transcript (splice variant), 235 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
BRL1YHR036W_mRNA1416471aaYHR036W
 
Protein coding
P38770 NM_001179166.1
NP_011901.1

Gene-based displays