Saccharomyces cerevisiae (R64-1-1)

Subunit of the Iml1p/SEACIT complex; SEACIT (Iml1p-Npr2p-Npr3p) is a subcomplex of SEAC, a coatomer-related complex that associates dynamically with the vacuole; Npr3p may have a structural or regulatory role, supporting Iml1p function as a GAP for the Rag family GTPase Gtr1p, and leading to inhibition of TORC1 signaling in response to amino acid deprivation; SEACIT is required for non-nitrogen-starvation-induced autophagy; null mutant has meiotic defects; human NPRL3 homolog [Source:SGD;Acc:S000001015]

Gene Synonyms



Chromosome VIII: 59,123-62,563 reverse strand.


About this gene

This gene has 1 transcript (splice variant) and 334 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P38742 -Ensembl Canonical