Saccharomyces cerevisiae (R64-1-1)

Ceramide synthase component; involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p; forms ER foci upon DNA replication stress; homolog of human CERS2, a tumor metastasis suppressor gene whose silencing enhances invasion/metastasis of prostate cancer cells; LAG1 has a paralog, LAC1, that arose from the whole genome duplication [Source:SGD;Acc:S000000995]


Chromosome VIII: 100,648-101,883 reverse strand.


About this gene

This gene has 1 transcript (splice variant), 428 orthologues and 1 paralogue.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P38703 -Ensembl Canonical