Highly conserved subunit of the mitochondrial pyruvate carrier (MPC); expressed during growth on nonfermentable carbon sources, and heterodimerizes with Mpc1p to form the respiratory isoform of MPC; MPC localizes to the mitochondrial inner membrane and mediates pyruvate uptake; MPC3 paralog, MPC2, heterodimerizes with Mpc1p to form the fermentative MPC isoform; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003475]
Chromosome VII: 977,336-977,776 forward strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 337 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.