Highly conserved subunit of the mitochondrial pyruvate carrier (MPC); expressed during growth on nonfermentable carbon sources, and heterodimerizes with Mpc1p to form the respiratory isoform of MPC; MPC localizes to the mitochondrial inner membrane and mediates pyruvate uptake; MPC3 paralog, MPC2, heterodimerizes with Mpc1p to form the fermentative MPC isoform; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003475]
Chromosome VII: 977,336-977,776 forward strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 337 orthologues and 2 paralogues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
MPC3 | YGR243W_mRNA | 441 | 146aa | YGR243W | Protein coding | P53311 | - | Ensembl Canonical, |