Squalene epoxidase; catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine; human SQLE functionally complements the lethality of the erg1 null mutation [Source:SGD;Acc:S000003407]
Chromosome VII: 846,933-848,423 reverse strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 377 orthologues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
ERG1 | YGR175C_mRNA | 1491 | 496aa | YGR175C | Protein coding | P32476 | - | Ensembl Canonical, |