Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR) [Source:SGD;Acc:S000003364]
Chromosome VII: 755,589-756,452 reverse strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 362 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
PHB1 | YGR132C_mRNA | 864 | 287aa | YGR132C | Protein coding | P40961 | NM_001181261.3 NP_011648.3 | Ensembl Canonical, |