Separase, a caspase-like cysteine protease; promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibits protein phosphatase 2A-Cdc55p to promote mitotic exit; inhibited by Pds1p; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003330]

Chromosome VII: 682,566-687,458 reverse strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 304 orthologues and is a member of 1 Ensembl protein family.

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