Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p [Source:SGD;Acc:S000003221]

Chromosome VII: 25,718-27,484 reverse strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 373 orthologues and is a member of 2 Ensembl protein families.

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