mRNA-binding protein of the PUF family; binds to specific mRNAs, often in the 3' UTR; has broad specificity and binds to more than 1000 mRNAs (16% of the transcriptome); recruits the CCR4-NOT deadenylase complex to mRNAs along with Dhh1p and Dcp1p to promote deadenylation, decapping, and decay; also interacts with the Caf20p translational initiation repressor, affecting its mRNA target specificity [Source:SGD;Acc:S000003146]

HTR1, PUF5, UTH4

Chromosome VII: 167,352-170,571 forward strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 154 orthologues, 2 paralogues and is a member of 2 Ensembl protein families.

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