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Saccharomyces cerevisiae (R64-1-1)
Description

Endonuclease required for telomere elongation; required for telomeric 5' C-rich strand resection; involved in ds-break repair and processing hairpin DNA structures with the MRX complex; function requires sumoylation and phosphorylation; exists as inactive oligomers that are transiently released into smaller active units by phosphorylation; DNA damage triggers Sae2p removal, so active Sae2p is present only transiently; sequence and functional similarity with human CtIP/RBBP8 [Source:SGD;Acc:S000003143]

Gene Synonyms

COM1

Location

Chromosome VII: 173,285-174,322 reverse strand.

R64-1-1:BK006941.2

About this gene

This gene has 1 transcript (splice variant) and 17 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SAE2YGL175C_mRNA1038345aaYGL175C
 
Protein coding
P46946 -Ensembl Canonical