Saccharomyces cerevisiae (R64-1-1)
Description

Endonuclease required for telomere elongation; required for telomeric 5' C-rich strand resection; involved in ds-break repair and processing hairpin DNA structures with the MRX complex; function requires sumoylation and phosphorylation; exists as inactive oligomers that are transiently released into smaller active units by phosphorylation; DNA damage triggers Sae2p removal, so active Sae2p is present only transiently; sequence and functional similarity with human CtIP/RBBP8 [Source:SGD;Acc:S000003143]

Synonyms

COM1

Location

Chromosome VII: 173,285-174,322 reverse strand.

R64-1-1:BK006941.2

About this gene

This gene has 1 transcript (splice variant) and 24 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SAE2YGL175C_mRNA1038345aaYGL175C
 
Protein coding
P46946 NM_001181040.1
NP_011340.1

Gene-based displays