Saccharomyces cerevisiae (R64-1-1)
Description

High affinity Ca2+/Mn2+ P-type ATPase; required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting, processing; D53A mutant (Mn2+ transporting) is rapamycin sensitive, Q783A mutant (Ca2+ transporting) is rapamycin resistant; Mn2+ transport into Golgi lumen required for rapamycin sensitivity; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease; human ATP2C1 can complement yeast null mutant [Source:SGD;Acc:S000003135]

Synonyms

BSD1, LDB1, SSC1

Location

Chromosome VII: 187,616-190,468 reverse strand.

R64-1-1:BK006941.2

About this gene

This gene has 1 transcript (splice variant), 338 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
PMR1YGL167C_mRNA2853950aaYGL167C
 
Protein coding
P13586 NM_001181032.1
NP_011348.1

Gene-based displays